Woulda. Coulda. Shoulda. That’s what a Next Big Thing is like. Footprints from your ass to the top of your head. Keep it in mind the next time the Valley Grail Quest gets trotted out by the punditocracy. There will eventually be a Valley 4.0, but the odds of any of the [experts] calling it in advance aren’t very wonderful. Most likely, it will hit rudely from behind, when least expected. So find something that solves problems for real people, gets you up in the morning, and lets you work with good folks, and dig in. That’s the way the Valley actually rejuvenates itself.
Food for thought, given that I don’t really know what I want to do next. These are three important things to look for, not necessarily to find the Next Big Thing, but to find a comfortable seat from which to watch for it.
BTW, I strongly recommend Due Diligence, an insightful, technology-focused blog written by a venture capitalist.